With support from the Center for the Advancement of Science in Space (CASIS), a team from University of California, Los Angeles (UCLA) and the Forsyth Institute shows that injecting mice with a bone-homing version of a bone growth-promoting protein can prevent space flight-induced bone loss.
Advances in space technology mean space travel will become more common for tourists as spaceflight passengers and for people looking to set up bases to explore the Moon and Mars. But can we study how space tourists, potentially with age and lifestyle-related chronic conditions will fare in space?
Our paper entitled, ''Mitigating sarcoplasmic reticulum stress limits disuse-induced muscle loss in hindlimb unloaded mice'' recently published in the NPJ Microgravity journal unravels the therapeutic potential of a drug to prevent muscle loss in microgravity conditions.
The Gravitational Recovery And Climate Experiment Follow-On (GRACE-FO) mission provides incredibly accurate measurements of changes in the Earth's gravitational field; important for climate scientists, oceanographers and geologists. In our paper, we propose new techniques to enhance such missions.
Our paper entitled “Transcriptional responses of skeletal stem/progenitor cells to hindlimb unloading and recovery correlate with localized but not systemic multi-systems impacts” just published in npj Microgravity, reveals how simulated microgravity alters bone at the stem/progenitor level.
Fine-tuning mechanism of "body building" in space microgravity environment with epigenetic modifications
Our paper entitled "Histone deacetylase HDA-4-mediated epigenetic regulation in space-flown C. elegans” just published in npj Microgravity, demonstrates a novel epigenetic modification in response to microgravity environment of space-grown C. elegans.
Enhancing biological performance by preventive and regenerative interventions for making humanity multiplanetary: Step 1 an antioxidant cocktail
Analysis of the Effects of Spaceflight and Local Administration of Thrombopoietin to a Femoral Defect Injury on Distal Skeletal Sites
Our recently published paper evidences a novel therapeutically approach for bone healing that improves osteogenesis in the absence of mechanical loading. Written by Ariane Zamarioli and Melissa Kacena